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Article

A TATA-binding protein mutant defective for TFIID complex formation in vivo.

Molecular and cellular biology - 1 Jun 1999

Ranallo R T, Struhl K, Stargell L A

Abstract excerpt

Using an intragenic complementation screen, we have identified a temperature-sensitive TATA-binding protein (TBP) mutant (K151L, K156Y) that is defective for interaction with certain yeast TBP-associated factors (TAFs) at the restrictive temperature. The K151L,K156Y mutant appears to be functional for RNA polymerase I (Pol I) and Pol III transcription, and it is capable of supporting Gal4-activated and...

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Source

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Identifiers

PMID: 10330135
DOI: 10.1128/MCB.19.6.3951
PMCID: PMC104354

Genes

TBP

Variants

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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