Article
Identification of highly conserved amino-terminal segments of dTAFII230 and yTAFII145 that are functionally interchangeable for inhibiting TBP-DNA interactions in vitro and in promoting yeast cell growth in vivo.
The Journal of biological chemistry - 27 Nov 1998
Kotani T, Miyake T, Tsukihashi Y, Hinnebusch A G, Nakatani Y, Kawaichi M, Kokubo T
Abstract excerpt
TFIID is a multiprotein complex composed of TBP and several TAFIIs. Small amino-terminal segments (TAF N-terminal domain (TAND)) of Drosophila TAFII230 (dTAFII230) and yeast TAFII145 (yTAFII145) bind strongly to TBP and inhibit TBP-DNA interactions. yTAFII145 TAND (yTAND) was divided into two sub...
Topics
- Amino Acid Sequence
- Animals
- Conserved Sequence
- DNA, Fungal
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Fungal Proteins
- Genotype
- Histone Acetyltransferases
- Humans
- Insect Proteins
- Molecular Sequence Data
- Phenotype