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Article

Molecular Genetic Alterations in Radiation-Induced Astrocytomas

1 May 1999

Abstract excerpt

Astrocytic tumors occasionally arise in the central nervous system following radiotherapy. It is not clear if these gliomas represent a unique molecular genetic subset. We identified nine cases in which an astrocytoma arose within ports of previous radiation therapy, with total doses ranging from 2400 to 5500 cGy. Irradiated primary lesions included craniopharyngioma, pituitary adenoma, Hodgkin's lymphoma,...

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PMID: 10329596
DOI: 10.1016/s0002-9440(10)65397-7

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