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Article

A Molecular Genetic Model of Astrocytoma Histopathology

1 Apr 1997

Abstract excerpt

As the molecular events responsible for astrocytoma formation and progression are being clarified, it is becoming possible to correlate these alterations with the specific histopathological and biological features of astrocytoma, anaplastic astrocytoma and glioblastoma multiforme. In WHO grade II astrocytomas, autocrine stimulation by the plateletderived growth factor system coupled with inactivation of the p53...

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PMID: 9161727
DOI: 10.1111/j.1750-3639.1997.tb01062.x

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