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Article

Mutation analysis of CYP11B1 and CYP11B2 in patients with increased 18-hydroxycortisol production.

Molecular and cellular endocrinology - 12 Feb 2004

Nicod Jérôme, Dick Bernhard, Frey Felix J, Ferrari Paolo

Abstract excerpt

BACKGROUND: In patients with glucocorticoid remediable aldosteronism (GRA), a rare hypertensive disorder caused by the presence of a chimeric aldosterone synthase (CYP11B2) and 11beta-hydroxylase (CYP11B1) gene, high level of urinary 18-hydroxycortisol (18OHF) excretion are observed. In some patients with hypertension, increased urinary 18OHF secretion is also found in the absence of the hybrid CYP11B1/CYP11B2...

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Share to Cytochrome P-450 CYP11B2
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gas Chromatography-Mass Spectrometry

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Source

Identifiers

PMID: 15062555
DOI: 10.1016/j.mce.2003.10.056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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