Article
The association between Trp64Arg polymorphism of the beta3-adrenergic receptor and autonomic nervous system activity.
The Journal of clinical endocrinology and metabolism - 1 May 1999
Shihara N, Yasuda K, Moritani T, Ue H, Adachi T, Tanaka H, Tsuda K, Seino Y
Abstract excerpt
The beta3-adrenergic receptor plays a significant role in the control of lipolysis and thermogenesis in brown adipose tissue through autonomic nervous system (ANS) activity. As the Trp64Arg polymorphism of the beta3-adrenergic receptor gene might affect ANS activity, we investigated the association of the polymorphism with ANS activity. The prevalence of the polymorphism was determined in 204 subjects. Ten normal...
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