Article
Assessing accuracy in linkage analysis by means of confidence regions.
Genetic epidemiology - 1 Jul 2003
Hössjer Ola
Abstract excerpt
When statistical linkage to a certain chromosomal region has been found, it is of interest to develop methods quantifying the accuracy with which the disease locus can be mapped. In this paper, we investigate the performance of three different types of confidence regions, with asymptotically correct coverage probability as the number of pedigrees grows. Our setup is that of a saturated map of marker data. We...
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