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Article

Too late for the midwife toad: stress, variability and Hsp90.

Trends in genetics : TIG - 1 May 1999

McLaren A

Abstract excerpt

In the 1940s and 1950s, Waddington put forward his theories of canalization and genetic assimilation. These provided a genetic basis to account for the inheritance of some apparently 'acquired' characters. Rutherford and Lindquist have now provided a molecular framework for these theories. Their results are also relevant to observations from the 1950s concerning homozygosity and variability, with a bearing on...

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Identifiers

PMID: 10322481
DOI: 10.1016/s0168-9525(99)01732-1

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