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Article

The role of HSP90 in evolution.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Jul 1999

Yahara I

Abstract excerpt

A mechanism by which morphological mutations are stored without expressing phenotypes was unraveled by Rutherford & Lindquist (1998) through genetic studies of Hsp83 (HSP90) in Drosophila. Cryptic mutations are essentially neutral and therefore evolve in the absence of selective constraint. A shift from neutral mutations to selective mutations is induced when flies are exposed to environmental stress. This is a...

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Identifiers

PMID: 10469170
DOI: 10.1046/j.1365-2443.1999.00271.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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