Article
Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays.
Molecular microbiology - 1 May 1999
Gordon S V, Brosch R, Billault A, Garnier T, Eiglmeier K, Cole S T
Abstract excerpt
Whole-genome comparisons of the tubercle bacilli were undertaken using ordered bacterial artificial chromosome (BAC) libraries of Mycobacterium tuberculosis and the vaccine strain, Mycobacterium bovis BCG-Pasteur, together with the complete genome sequence of M. tuberculosis H37Rv. Restriction-digested BAC arrays of M. tuberculosis H37Rv were used in hybridization experiments with radiolabelled M. bovis BCG...
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