Article
Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant.
Infection and immunity - 1 Oct 2002
Brodin Priscille, Eiglmeier Karin, Marmiesse Magali, Billault Alain, Garnier Thierry, Niemann Stefan, Cole Stewart T, Brosch Roland
Abstract excerpt
Mycobacterium microti is a member of the Mycobacterium tuberculosis complex that causes tuberculosis in voles. Most strains of M. microti are harmless for humans, and some have been successfully used as live tuberculosis vaccines. In an attempt to identify putative virulence factors of the tubercle bacilli, genes that are absent from the avirulent M. microti but present in human pathogen M. tuberculosis or...
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