Article
Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis.
Journal of bacteriology - 1 Mar 1996
Mahairas G G, Sabo P J, Hickey M J, Singh D C, Stover C K
Abstract excerpt
The live attenuated bacillus Calmette-Guérin (BCG) vaccine for the prevention of disease associated with Mycobacterium tuberculosis was derived from the closely related virulent tubercle bacillus, Mycobacterium bovis. Although the BCG vaccine has been one of the most widely used vaccines in the w...
Topics
- BCG Vaccine
- Base Sequence
- Blotting, Southern
- Cloning, Molecular
- Gene Expression
- Genome, Bacterial
- Molecular Sequence Data
- Mutation
- Mycobacterium bovis
- Open Reading Frames
- Restriction Mapping
- Sequence Deletion
- Vaccines, Attenuated
- Virulence