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Article

Contribution of Horizontally Acquired Genomic Islands to the Evolution of the Tubercle Bacilli

18 Apr 2007

Abstract excerpt

The contribution of horizontal gene transfer (HGT) to the evolution of Mycobacterium tuberculosis -- the main causal agent of tuberculosis in humans -- and closely related members of the M. tuberculosis complex remains poorly understood. Using a combination of genome-wide parametric analyses, we have identified 48 M. tuberculosis chromosomal regions with atypical characteristics, potentially due to HGT. These...

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PMID: 17545187
DOI: 10.1093/molbev/msm111

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