Article
Venous thromboembolic disease and the prothrombin, methylene tetrahydrofolate reductase and factor V genes.
Thrombosis and haemostasis - 1 Apr 1999
Alhenc-Gelas M, Arnaud E, Nicaud V, Aubry M L, Fiessinger J N, Aiach M, Emmerich J
Abstract excerpt
The prevalence of the A20210 allele of the prothrombin (PT) gene and the T677 allele of the methylene tetrahydrofolate reductase (MTHFR) gene was determined in 205 patients with venous thromboembolism (VTE) and in 398 healthy subjects of similar age and sex distribution. We also determined the frequency of these two candidate risk alleles in subjects carrying the factor V (FV) Q506 allele, to identify a possible...
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