Genetic susceptibility to pregnancy-related venous thromboembolism: roles of factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations.

doi:10.1016/s0002-9378(98)70155-3

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Article

Genetic susceptibility to pregnancy-related venous thromboembolism: roles of factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations.

American journal of obstetrics and gynecology - 1 Nov 1998

Grandone E, Margaglione M, Colaizzo D, D'Andrea G, Cappucci G, Brancaccio V, Di Minno G

Abstract excerpt

OBJECTIVE: This study's objective was to evaluate the association between venous thromboembolism during pregnancy and the postpartum period and the factor V Arg 506 Gln (factor V Leiden), the prothrombin G20210A, and methylenetetrahydrofolate reductase C677T polymorphisms. STUDY DESIGN: In this c...

Topics

Adult
Base Sequence
Case-Control Studies
Factor V
Female
Genetic Carrier Screening
Genetic Predisposition to Disease
Homozygote
Humans
Methylenetetrahydrofolate Reductase (NADPH2)
Mutation
Oxidoreductases Acting on CH-NH Group Donors
Pregnancy

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pregnancy Complications, Cardiovascular

Prothrombin

Pulmonary Embolism

Thromboembolism

Venous Thrombosis

Source

Open in PubMed

Identifiers

PMID: 9822524
DOI: 10.1016/s0002-9378(98)70155-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9822524-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.