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THROMBOTIC RISK EVALUATION OF TWO METHYLENETETRAHYDROFOLATE REDUCTASE MUTATIONS C677t AND A1298c IN VENOUS THROMBOEMBOLISM.

Acta clinica Croatica - 1 Jun 2025

Kundid Renata, Kolundžić Monika, Babić Ivana, Kereš Tatjana, Svaguša Tomo, Bingulac-Popović Jasna, Hećimović Ana, Jukić Irena

Abstract excerpt

The MTHFR mutations C677T and A1298C combined with folate and vitamin B12 deficiency lead to hypercoagulability. We evaluated thrombotic risk due to MTHFR mutations, individually and in combination, in patients with venous thromboembolism (VTE). The case-control study included groups of 262 VTE patients and 101 healthy controls. Allelic distribution of MTHFR C677T/A1298C mutations was determined by real-time...

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Identifiers

PMID: 41635665
DOI: 10.20471/acc.2025.64.02.07
PMCID: PMC12863379

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MTHFR

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THROMBOTIC RISK EVALUATION OF TWO METHYLENETETRAHYDROFOLATE REDUCTASE MUTATIONS C677t AND A1298c IN VENOUS THROMBOEMBOLISM.PMID 41635665Read ↗

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