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Article

N-acetyltransferase-2, glutathione S-transferase M1, alcohol dehydrogenase, and cytochrome P450IIE1 genotypes in alcoholic liver cirrhosis: a case-control study.

Scandinavian journal of gastroenterology - 1 Mar 1999

Rodrigo L, Alvarez V, Rodriguez M, Pérez R, Alvarez R, Coto E

Abstract excerpt

BACKGROUND: Only a small percentage of long-term alcoholics develop liver cirrhosis. Genetic and non-genetic factors have been implicated in the risk of developing this disease. Among the genetic factors, case-control studies suggest an association with some polymorphisms at the alcohol dehydrogenase and cytochrome P450IIE1 genes. N-Acetyltransferase-2 metabolizes multiple compounds, transforming some of them to...

Read the complete abstract on PubMed

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Share to Acetylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Arylamine N-Acetyltransferase

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Share to Liver Cirrhosis, Alcoholic

Source

Identifiers

PMID: 10232877
DOI: 10.1080/00365529950173735

Genes

GSTM1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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