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N-Acetyltransferase 2, glutathione S-transferase gene polymorphisms and susceptibility to hepatocellular carcinoma in an Algerian population.

Xenobiotica; the fate of foreign compounds in biological systems - 1 Jan 2022

Chorfi Lamia, Fercha Azzedine, Derouiche Faouzia, Sebihi Fatima Zohra, Houhou Dallal, Chorfi Keltoum, Bendjemana Katia

Abstract excerpt

This study was conducted to investigate the potential association of genetic polymorphisms of glutathione S-transferase M1/T1 (GSTM1, GSTT1), and N-acetyltransferase 2 (NAT2) genes and epidemiological parameters with the risk of HCC in the Algerian population.A case-control study including 132 confirmed HCC patients and 141 cancer-free controls was performed. Genotyping analysis was performed using conventional...

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PMID: 35138223
DOI: 10.1080/00498254.2022.2040642

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