Article
Genetic susceptibility and transmission factors in scrapie: detailed analysis of an epidemic in a closed flock of Romanov.
Archives of virology - 1 Jan 1999
Elsen J M, Amigues Y, Schelcher F, Ducrocq V, Andreoletti O, Eychenne F, Khang J V, Poivey J P, Lantier F, Laplanche J L
Abstract excerpt
Information from a scrapie epidemic in a closed INRA Romanov flock is presented. Performances, pedigree, histopathological diagnoses and PrP genotypes were recorded from the beginning of the outbreak (in 1993). Between 1st of April, 1993 and 1st of May, 1997, 1015 animals were exposed to scrapie, and 304 died from this disease. A major influence of the polymorphisms at codons 136, 154 and 171 is shown,...
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