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Article

Mixed-lineage leukemia with t(10;11)(p13;q21): An analysis ofAF10-CALM andCALM-AF10 fusion mRNAs and clinical features

1 May 1999

Abstract excerpt

A fusion transcript of AF10 and CALM was isolated recently from the U937 cell line with t(10;11)(p13;q21). We performed reverse transcription-polymerase chain reaction and sequencing analysis on the t(10;11) leukemia samples obtained from four patients and one cell line, and we identified reciprocal fusion transcripts of AF10 and CALM in all the samples. The fusion transcripts in the five samples showed four...

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Identifiers

PMID: 10221337
DOI: 10.1002/(sici)1098-2264(199905)25:1<33::aid-gcc5>3.0.co;2-3

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Mixed-lineage leukemia with t(10;11)(p13;q21): An analysis ofAF10-CALM andCALM-AF10 fusion mRNAs and clinical featuresPMID 10221337Read ↗

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A novel gene, AF1q, fused to MLL in t(1;11) (q21;q23), is specifically expressed in leukemic and immature hematopoietic cellsSemantic proximity Read ↗

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