Article
The C-terminal domain of dnaQ contains the polymerase binding site.
Journal of bacteriology - 1 May 1999
Taft-Benz S A, Schaaper R M
Abstract excerpt
The Escherichia coli dnaQ gene encodes the 3'-->5' exonucleolytic proofreading (epsilon) subunit of DNA polymerase III (Pol III). Genetic analysis of dnaQ mutants has suggested that epsilon might consist of two domains, an N-terminal domain containing the exonuclease and a C-terminal domain essential for binding the polymerase (alpha) subunit. We have created truncated forms of dnaQ resulting in epsilon subunits...
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