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Article

Structural studies of the interactions of normal and abnormal human plasmins with bovine basic pancreatic trypsin inhibitor.

Chemical & pharmaceutical bulletin - 1 Mar 1999

Takeda-Shitaka M, Kamiya K, Miyata T, Ohkura N, Madoiwa S, Sakata Y, Umeyama H

Abstract excerpt

Catalytic activity of human plasmin is inhibited by bovine basic pancreatic trypsin inhibitor (BPTI, also known as aprotinin). In spite of increased interest in the function of BPTI as an inhibitor of plasmin, the 3-D structure of the plasmin-BPTI complex has not yet been determined. Therefore, in the present paper, the structure of the plasmin-BPTI complex was constructed by the homology modeling method, which...

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Identifiers

PMID: 10212382
DOI: 10.1248/cpb.47.322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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