Article
A genealogical study of Alzheimer disease in the Saguenay region of Quebec.
Genetic epidemiology - 1 Jan 1999
Vézina H, Heyer E, Fortier I, Ouellette G, Robitaille Y, Gauvreau D
Abstract excerpt
We performed an analysis of inbreeding and kinship among the ascending genealogies of 205 autopsy-confirmed Alzheimer disease (AD) subjects recruited in the Saguenay area of Québec. We hypothesized that if some traits pertaining to the disease were determined by inherited factors, and if the corresponding genes were not too frequent in the population, it might be possible to detect some clusters of patients...
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