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Article

Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2018

Scholz Claus-Jürgen, Weber Heike, Jungwirth Susanne, Danielczyk Walter, Reif Andreas, Tragl Karl-Heinz, Fischer Peter, Riederer Peter, Deckert Jürgen, Grünblatt Edna

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative disorder that preferentially affects individuals of advanced age. Heritability estimates for AD range between 60 and 80%, but only few genetic risk factors have been identified so far. In the present explorative study, we aimed at characterizing the genetic contribution to late-onset AD in participants of the Vienna Transdanube Aging (VITA) longitudinal birth cohort...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29027019
DOI: 10.1007/s00702-017-1796-6

Genes

ADAMTS3
PPFIA1
QRFPR

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