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Article

Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53.

Molecular and cellular biology - 1 May 1999

Blattner C, Sparks A, Lane D

Abstract excerpt

The transcription factor E2F-1 directs the expression of genes that induce or regulate cell division, and a role for E2F-1 in driving cells into apoptosis is the subject of intense discussion. Recently it has been shown that E2F-1 binds and coprecipitates with the mouse double-minute chromosome 2 protein (Mdm2). A domain of E2F-1 (amino acids 390 to 406) shows striking similarity to the Mdm2 binding domain of the...

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Identifiers

PMID: 10207094
DOI: 10.1128/MCB.19.5.3704
PMCID: PMC84185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53.PMID 10207094Read ↗

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