Article
CTLA4 polymorphisms in Spanish patients with rheumatoid arthritis.
Tissue antigens - 1 Mar 1999
Gonzalez-Escribano M F, Rodriguez R, Valenzuela A, Garcia A, Garcia-Lozano J R, Nuñez-Roldan A
Abstract excerpt
Cytotoxic T-lymphocyte antigen 4 (CTLA4) polymorphisms located in the promotor region at positions -318 (C/T) and in exon 1 (49 A/ G) were investigated in 138 Spanish patients (37 men and 101 women) with rheumatoid arthritis and in 305 ethnically-matched healthy controls. When the allelic and genotypic frequencies corresponding to the CTLA4 -318 position were compared, no significant differences between patients...
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