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Article

Phenotypic alterations of small cell lung carcinoma induced by different levels of wild-type p53 expression.

Cell death and differentiation - 1 Feb 1998

Adachi J, Ookawa K, Kohno T, Tomizawa Y, Tsuchida S, Yokota J

Abstract excerpt

p53 induces both growth arrest and apoptosis in cancer cells. To clarify whether the level of p53 expression determines the response of small cell lung carcinoma (SCLC) cells, we assessed the effect of various p53 levels on a p53-null SCLC cell line, N417, using a tetracycline (Tc)-regulated indu...

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Identifiers

PMID: 10200459
DOI: 10.1038/sj.cdd.4400325

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10200459-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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