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Article

p53 gene status modulates the chemosensitivity of non-small cell lung cancer cells.

Journal of biomedical science - 1 Jan 2000

Lai S L, Perng R P, Hwang J

Abstract excerpt

This study examined the effects of p53 gene status on DNA damage-induced cell death and chemosensitivity to various chemotherapeutic agents in non-small cell lung cancer (NSCLC) cells. A mutant p53 gene was introduced into cells carrying the wild-type p53 gene and also vice versa to introduce the wild-type p53 gene into cells carrying the mutant p53 gene. Chemosensitivity and DNA damage-induced apoptosis in these...

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Source

Identifiers

PMID: 10644891
DOI: 10.1007/BF02255920

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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