Article
Administration of G-CSF to normal individuals diminishes L-selectin+ T cells in the peripheral blood that respond better to alloantigen stimulation than L-selectin- T cells.
Bone marrow transplantation - 1 Jan 1999
Sugimori N, Nakao S, Yachie A, Niki T, Takami A, Yamazaki H, Miura Y, Ueda M, Shiobara S, Matsuda T
Abstract excerpt
To determine whether administration of G-CSF induces phenotypic or functional changes in T cells, we examined peripheral blood T cells from normal individuals receiving G-CSF for activation antigen and adhesion molecule expression before and after G-CSF administration. G-CSF (10 microg/kg/day) was administered subcutaneously to 14 normal individuals for 3-5 days and their PBMC were serially analyzed with...
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