Article
T lymphocyte migration to lymph nodes is maintained during homeostatic proliferation.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada - 1 Jun 2008
Kodera Masanari, Grailer Jamison J, Karalewitz Andrew P-A, Subramanian Hariharan, Steeber Douglas A
Abstract excerpt
The immune system maintains appropriate cell numbers through regulation of cell proliferation and death. Normal tissue distribution of lymphocytes is maintained through expression of specific adhesion molecules and chemokine receptors such as L-selectin and CCR7, respectively. Lymphocyte insufficiency or lymphopenia induces homeostatic proliferation of existing lymphocytes to increase cell numbers. Interestingly,...
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