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Article

Mutations in Promoter Region of Thrombomodulin and Venous Thromboembolic Disease

1 Apr 1999

Abstract excerpt

The present study was designed to analyze the thrombomodulin proximal promoter region spanning nucleotides -293 to -12 to search for polymorphisms that could modify thrombomodulin gene expression in patients with venous thromboembolic disease. The study population comprised 205 patients and 394 healthy subjects of similar age and sex distribution. No polymorphisms and only 1 point mutation (G-33A) were found. The...

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Share to Blood Coagulation and Thrombosis Mechanisms
Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
Share to Venous Thromboembolism Diagnosis and Management

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Identifiers

PMID: 10195941
DOI: 10.1161/01.atv.19.4.1098

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