Article
G-33A mutation in the promoter region of thrombomodulin gene and its association with coronary artery disease and plasma soluble thrombomodulin levels.
The American journal of cardiology - 1 Jan 2000
Li Y H, Chen J H, Wu H L, Shi G Y, Huang H C, Chao T H, Tsai W C, Tsai L M, Guo H R, Wu W S, Chen Z C
Abstract excerpt
Thrombomodulin is an endothelial glycoprotein that decreases thrombin activity and activates protein C. A recent study has shown that G-33A promoter mutation of the thrombomodulin gene occurs particularly in Asians. In this study, we analyzed the distribution of G-33A mutation in the promoter region of the thrombomodulin gene in the Chinese population and determined whether the mutation might be a risk for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.