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Article

Contribution of topoisomerase IV mutation to quinolone resistance in Mycoplasma genitalium.

Antimicrobial agents and chemotherapy - 1 Apr 2013

Yamaguchi Yuko, Takei Masaya, Kishii Ryuta, Yasuda Mitsuru, Deguchi Takashi

Abstract excerpt

The mechanism of quinolone resistance in Mycoplasma genitalium remains poorly understood due to difficulties with in vitro culture, especially of clinical isolates. In this study, to confirm the association between mutations in topoisomerases and antimicrobial susceptibilities to quinolones, ciprofloxacin-resistant mutant strains were selected using the cultivable type strain ATCC 33530. Sequence analysis...

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Source

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Identifiers

PMID: 23357772
DOI: 10.1128/AAC.01956-12
PMCID: PMC3623360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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