Article
The spectrum of growth-hormone insensitivity.
The Journal of pediatrics - 1 Jul 1997
Parks J S, Brown M R, Faase M E
Abstract excerpt
OBJECTIVES: To summarize the steps that led to the recognition of the Laron syndrome of growth-hormone (GH) insensitivity as a recessive disorder that is caused by mutations in the growth hormone receptor (GHR) gene, to discuss the different types of mutations that have been found in the GHR gene...
Topics
- Age Factors
- Base Composition
- Body Height
- Codon, Nonsense
- Exons
- Gene Deletion
- Genes, Recessive
- Growth Disorders
- Heterozygote
- Homozygote
- Human Growth Hormone
- Humans
- Mutation