Article
Association between the T102C polymorphism of the serotonin-2A receptor gene and schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry - 30 Aug 2006
Vaquero Lorenzo Concepcion, Baca-Garcia Enrique, Diaz-Hernandez Montserrat, Botillo-Martin Carlota, Perez-Rodriguez M Mercedes, Fernandez-Ramos Carolina, Saiz-Gonzalez M Dolores, Quintero-Gutierrez Francisco J, Saiz-Ruiz Jeronimo, Fernandez Piqueras Jose, Gonzalez de Rivera Jose Luis, de Leon Jose
Abstract excerpt
Studies have shown an association between the T102C polymorphism of the 5HT2a receptor gene and schizophrenia. However, negative findings have also been reported. We conducted a case-control study of the T102C polymorphism in Spanish Caucasians. We compared T102C polymorphism genotypes and allele frequencies in 188 schizophrenia patients and 440 healthy controls. There were significant differences in the...
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