Article
H-Ras is a negative regulator of alpha3beta1 integrin expression in ECV304 endothelial cells.
Biochemical and biophysical research communications - 2 Apr 1999
Shin E Y, Lee J Y, Park M K, Jeong G B, Kim E G, Kim S Y
Abstract excerpt
We have examined the role of Ras in integrin expression in ECV304 endothelial cells. Among the integrins examined in stable ECV304 transfectants expressing dominant active H-Ras (DAR-ECV), expression of alpha3beta1 integrin showed a prominent reduction in all the DAR-ECV clones when compared to the parental ECV304 cells. This implies that H-Ras negatively regulates the expression of alpha3beta1 integrin in ECV304...
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