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Article

Differential effects of CC chemokines on CC chemokine receptor 5 (CCR5) phosphorylation and identification of phosphorylation sites on the CCR5 carboxyl terminus.

The Journal of biological chemistry - 26 Mar 1999

Oppermann M, Mack M, Proudfoot A E, Olbrich H

Abstract excerpt

The binding of CC chemokines to CC chemokine receptor 5 (CCR5) triggers cellular responses that, generally, are only transient in nature. To explore the potential role of G protein-coupled receptor kinases (GRKs) in the regulation of CCR5, we performed phosphorylation experiments in a rat basophi...

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Source

Identifiers

PMID: 10085131
DOI: 10.1074/jbc.274.13.8875

Genes

CCR5
GRK2
CCR1
GRK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10085131-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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