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Article

Chimeric receptors of the human C3a receptor and C5a receptor (CD88).

The Journal of biological chemistry - 26 Mar 1999

Crass T, Ames R S, Sarau H M, Tornetta M A, Foley J J, Köhl J, Klos A, Bautsch W

Abstract excerpt

Chimeras were generated between the human anaphylatoxin C3a and C5a receptors (C3aR and C5aR, respectively) to define the structural requirements for ligand binding and discrimination. Chimeric receptors were generated by systematically exchanging between the two receptors four receptor modules (the N terminus, transmembrane regions 1 to 4, the second extracellular loop, and transmembrane region 5 to the C...

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Identifiers

PMID: 10085065
DOI: 10.1074/jbc.274.13.8367

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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