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Phylogenetic analysis of mitochondrial DNA in type 2 diabetes: maternal history and ancient population expansion.

Diabetes - 1 Mar 1999

Sherratt E J, Thomas A W, Gill-Randall R, Alcolado J C

Abstract excerpt

Several studies have suggested a maternal excess in the transmission of type 2 (non-insulin-dependent) diabetes. However, the majority of these reports rely on patients recalling parental disease status and hence are open to criticism. An alternative approach is to study mitochondrial DNA (mtDNA) lineages. The hypervariable region 1 of the rapidly evolving noncoding section of mtDNA is suitable for investigating...

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Identifiers

PMID: 10078567
DOI: 10.2337/diabetes.48.3.628

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Source receipt: pubmed, retrieved 7 Sept 2026.

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