Article
Contribution of interleukin 1beta and KM loci to alopecia areata.
Human heredity - 1 Mar 1999
Galbraith G M, Palesch Y, Gore E A, Pandey J P
Abstract excerpt
Alopecia areata is a common skin disease in which proinflammatory cytokines such as IL-1beta may play a pathogenic role. In this study, we examined the distribution of genotypes of an IL-1beta single base change polymorphism at position +3953 in patients with alopecia areata. The distribution of immunoglobulin kappa light chain (KM) genotypes was similarly examined. The data obtained showed that the IL-1beta and...
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