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Article

The MCP-1 rs1024611 and MTHFR rs1801133 gene variations and expressions in alopecia areata: A pilot study.

Immunity, inflammation and disease - 1 Feb 2022

Tabatabaei-Panah Pardis-Sadat, Moravvej Hamideh, Hajihasani Mahsa, Mousavi Mahsa, Ludwig Ralf J, Akbarzadeh Reza

Abstract excerpt

BACKGROUND: Monocyte chemoattractant protein-1 (MCP-1) is highly expressed by lymphocytes at skin sites affected by alopecia areata (AA). Variations in MCP-1 as well as in methylene-tetrahydrofolate reductase (MTHFR), a key enzyme related to many inflammatory pathologies, have been associated with several autoimmune disorders. This study was designed to test a possible association between MCP-1 and MTHFR...

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Identifiers

PMID: 34752683
DOI: 10.1002/iid3.564
PMCID: PMC8767509

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