A functional polymorphism in interleukin-1α (IL1A) gene is associated with risk of alopecia areata in Chinese populations.

doi:10.1016/j.gene.2013.02.048

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Article

A functional polymorphism in interleukin-1α (IL1A) gene is associated with risk of alopecia areata in Chinese populations.

Gene - 1 Jun 2013

Lu Dandan, Chen Lingling, Shi Xin, Zhang Xiaoting, Ling Xin, Chen Xiaojian, Xie Lixia, Jiang Lingling, Ding Lan, He Yan, Zhang Xingqi

Abstract excerpt

Alopecia areata (AA) is an inflammatory hair loss disorder with a major genetic component, which may cause great psychosocial distress for those affected. Studies have shown that interleukin-1 (IL-1) is a very potent inducer of hair loss and a significant human hair growth inhibitor. The 4-bp insertion/deletion (Indel) polymorphism (rs3783553) within the 3' untranslated regions of IL1A gene has been suggested to...

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PMID: 23542780
DOI: 10.1016/j.gene.2013.02.048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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