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Article

Transgenic Interleukin 10 Prevents Induction of Experimental Autoimmune Encephalomyelitis

15 Mar 1999

Abstract excerpt

The effectiveness of interleukin 10 (IL-10) in the treatment of autoimmune-mediated central nervous system inflammation is controversial. Studies of the model system, experimental autoimmune encephalomyelitis (EAE), using various routes, regimens, and delivery methods of IL-10 suggest that these variables may affect its immunoregulatory function. To study the influence of these factors on IL-10 regulation of EAE...

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PMID: 10075984
DOI: 10.1084/jem.189.6.1005

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