Islet cell antibodies in Sulawesi macaques.

Abstract excerpt

Older monkeys of the Sulawesian species Macaca nigra spontaneously develop a lesion in the pancreatic islets of Langerhans in which there is deposition of amyloid and gradual degeneration of all cells, which can lead eventually to development of diabetes mellitus. Islet cell antibodies (ICA), formed in response to the release of cellular antigens, can be used to detect the islet lesion and to monitor the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antibodies
• Share to Diabetes Mellitus
• Share to Disease Progression