Article
Association analysis of a highly polymorphic CAG Repeat in the human potassium channel gene KCNN3 and migraine susceptibility.
BMC medical genetics - 14 Sept 2005
Curtain Robert, Sundholm James, Lea Rod, Ovcaric Mick, MacMillan John, Griffiths Lyn
Abstract excerpt
BACKGROUND: Migraine is a polygenic multifactorial disease, possessing environmental and genetic causative factors with multiple involved genes. Mutations in various ion channel genes are responsible for a number of neurological disorders. KCNN3 is a neuronal small conductance calcium-activated potassium channel gene that contains two polyglutamine tracts, encoded by polymorphic CAG repeats in the gene. This gene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
