Article
Impact of p16 expression on surgical management of malignant melanoma and pancreatic carcinoma.
American journal of surgery - 1 Jan 1999
Bullock G J, Green J L, Baron P L
Abstract excerpt
BACKGROUND: Recent advances in molecular oncology have provided explanations at the DNA level for the malignant transformation and metastatic potential of various cancers. Malignant melanoma and pancreatic cancer may be classified together in both these cancers exhibit mutations in, or loss of, the cell-cycle inhibitory gene, p16. This paper reviews the current literature on p16 expression in melanoma and...
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