Article
Genetic framework of cyclin-dependent kinase function in Arabidopsis.
Developmental cell - 15 May 2012
Nowack Moritz K, Harashima Hirofumi, Dissmeyer Nico, Zhao Xin'Ai, Bouyer Daniel, Weimer Annika K, De Winter Freya, Yang Fang, Schnittger Arp
Abstract excerpt
Cyclin-dependent kinases (CDKs) are at the heart of eukaryotic cell-cycle control. The yeast Cdc2/CDC28 PSTAIRE kinase and its orthologs such as the mammalian Cdk1 have been found to be indispensable for cell-cycle progression in all eukaryotes investigated so far. CDKA;1 is the only PSTAIRE kinase in the flowering plant Arabidopsis and can rescue Cdc2/CDC28 mutants. Here, we show that cdka;1 null mutants are...
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