Complex traits on the map.

Abstract excerpt

The lod score method for localizing mendelian disease genes in human genetics is reviewed. Current ways of applying this technique to hypothesized genes underlying complex traits are discussed. In contrast to these parametric methods, allele-sharing methods using affected sib pairs are reviewed. Based on such allele-sharing data, a particular type of analysis is outlined which can identify sets of disease loci....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Neural Networks, Computer
• Share to Alleles
• Share to Chromosome Mapping