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Article

White matter lesion load increases the risk of low CSF Aβ42 in apolipoprotein E-ɛ4 carriers attending a memory clinic.

Journal of neuroimaging : official journal of the American Society of Neuroimaging - 1 Apr 2011

Stenset Vidar, Hofoss Dag, Johnsen Lisbeth, Berstad Audun Elnaes, Negaard Anne, Skinningsrud Anders, Gjerstad Leif, Fladby Tormod

Abstract excerpt

BACKGROUND: White matter lesions (WMLs) are age-related manifestations of ischemic cerebrovascular disease and increase the risk for Alzheimer's disease (AD). The apolipoprotein E (ApoE) ɛ4 allele is a risk factor for late onset AD and has been related to low cerebrospinal fluid (CSF) Aβ42 levels and to cerebrovascular disease. The present study analyzed the relationship between WMLs, ApoE-ɛ4 genotype, and low...

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Identifiers

PMID: 19888930
DOI: 10.1111/j.1552-6569.2009.00444.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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