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Article

Early embryonic death of mice deficient in gamma-adaptin.

The Journal of biological chemistry - 26 Feb 1999

Zizioli D, Meyer C, Guhde G, Saftig P, von Figura K, Schu P

Abstract excerpt

Intracellular protein transport and sorting by vesicles in the secretory and endocytic pathways requires the formation of a protein coat on the membrane. The heterotetrameric adaptor protein complex 1 (AP-1) promotes the formation of clathrin-coated vesicles at the trans-Golgi network. AP-1 interacts with various sorting signals in the cytoplasmic tails of cargo molecules, thus indicating a function in protein...

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Identifiers

PMID: 10026148
DOI: 10.1074/jbc.274.9.5385

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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